Pentafluorobenzoyl chloride

Base Information

  • Chemical Name: Pentafluorobenzoyl chloride
  • CAS No.: 2251-50-5

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1.What is the Pentafluorobenzoyl chloride ?

Pentafluorobenzoyl chloride can be used for the derivatization of a variety of analytes including biological amines. There is an extensive use for the derivatization of lipids.

Pentafluorobenzoic acid
602-94-8

Pentafluorobenzoic acid

pentafluorobenzoylchloride
2251-50-5

pentafluorobenzoylchloride

Conditions
Conditions Yield
With thionyl chloride; for 2h; Reflux;
100%
With thionyl chloride; for 3h; Reflux;
99%
With phosphorus pentachloride;
78%
With phosphorus pentachloride; for 2h; Reflux;
75%
With thionyl chloride; Heating;
With phosphorus pentachloride;
With thionyl chloride; N,N-dimethyl-formamide; In chloroform; for 1h; Heating;
With thionyl chloride; N,N-dimethyl-formamide; In toluene; at 60 - 70 ℃;
With thionyl chloride;
With thionyl chloride; for 12h; Heating;
With thionyl chloride; In toluene;
With thionyl chloride; In N,N-dimethyl-formamide; at 80 - 90 ℃; for 17h;
With thionyl chloride; for 2h; Heating;
With thionyl chloride; for 20h; Heating;
With chloroformic acid ethyl ester; triethylamine; In dichloromethane; at 0 ℃; for 0.5h;
With thionyl chloride; N,N-dimethyl-formamide; at 20 ℃; for 10h; Inert atmosphere;
With thionyl chloride; for 4h; Reflux;
With thionyl chloride; In N,N-dimethyl-formamide; Inert atmosphere; Reflux;
With thionyl chloride; Reflux;
With thionyl chloride; In dichloromethane; for 4h; Reflux;
With sulfuryl dichloride; for 3h; Reflux;
With thionyl chloride; In dichloromethane;
With thionyl chloride; at 20 ℃; for 12h;
With oxalyl dichloride; N,N-dimethyl-formamide; In dichloromethane; at 20 ℃; for 2h; Inert atmosphere;
With oxalyl dichloride; N,N-dimethyl-formamide; In dichloromethane; at 0 - 30 ℃; for 3h;
With thionyl chloride; In N,N-dimethyl-formamide;
With oxalyl dichloride; N,N-dimethyl-formamide; In dichloromethane; at 0 - 20 ℃;
Pentafluorobenzoic acid
602-94-8

Pentafluorobenzoic acid

1,2,3,4,5-pentafluoro-6-(trichloromethyl)benzene
778-34-7

1,2,3,4,5-pentafluoro-6-(trichloromethyl)benzene

pentafluorobenzoylchloride
2251-50-5

pentafluorobenzoylchloride

Conditions
Conditions Yield
With iron(III) oxide; at 142 ℃; for 2.5h; Autoclave;
96.3%

2.What is the CAS number for Pentafluorobenzoyl chloride ?

The CAS number of Pentafluorobenzoyl chloride is 2251-50-5.

More information of Pentafluorobenzoyl chloride 2251-50-5 are:

CAS?Number

2251-50-5

Density

1.684 g/cm3

Boiling Point

158.504 °C at 760 mmHg

Flash Point

49.662 °C

Vapor Pressure

2.91E-06mmHg at 25°C

Refractive Index

n20/D 1.453(lit.)

HS CODE

29163900

PSA

17.07000

LogP

2.76110

3.What are another words for Pentafluorobenzoyl chloride ?

Synonyms?for?Pentafluorobenzoyl chloride 2251-50-5:Benzoylchloride, pentafluoro- (6CI,7CI,8CI,9CI);2,3,4,5,6-Pentafluorobenzoic acidchloride;2,3,4,5,6-Pentafluorobenzoyl chloride;NSC 97002;Perfluorobenzoyl chloride;

4.What is the molecular formula of Pentafluorobenzoyl chloride?

The chemical formula of ?Pentafluorobenzoyl chloride is?C7ClF5O which containing 7 Carbon atoms,1 Chlorine atoms,5 Fluorine atoms and 1 Oxygen atoms,and the molecular weight of??Pentafluorobenzoyl chloride?is 230.521.

5.What is Pentafluorobenzoyl chloride (2251-50-5) used for?

Pentafluorobenzoyl chloride is the acid chloride of pentafluorobenzoic acid. It is a sensitive derivatising reagent for the analysis of amines, amides and phenols by electron capture gas chromatography. It has a role as a chromatographic reagent. It is an acyl chloride and a perfluorinated compound. It derives from a pentafluorobenzoic acid.2,3,4,5,6-Pentafluorobenzoyl chloride was used for derivatization of 5-androstenediol, testosterone, estradiol , dihydrotestosterone and estrone in a study to determine their serum levels. 2,3,4,5,6-Pentafluorobenzoyl chloride was used to derivatize dimethylamine(DMA) in study to develop a rapid and accurate GC–MS method for determination of DMA in human urine. 2,3,4,5,6-Pentafluorobenzoyl chloride was used in a study to detect the presence of Enterobacter cloacae in cultures of Leuconostoc mesenteroide by gas chromatography/mass spectrometry.

InChI:InChI=1/C10H28N6.C2H4O2/c11-1-3-13-5-7-15-9-10-16-8-6-14-4-2-12;1-2(3)4/h13-16H,1-12H2;1H3,(H,3,4)

Relevant articles related to Pentafluorobenzoyl chloride:

Article

Source

Fluorocontaining Heterocycles: IX. Derivatives of Imidazo[2,1-b][1,3] benzothiazine

Lipunova,Nosova,Mokrushina,Ogloblina,Aleksandrov,Charushin

, p. 248 - 256 (2003)

Synthesis of N-trifluoromethyl amides from carboxylic acids

Flavell, Robert R.,Liu, Jianbo,Parker, Matthew F. L.,Toste, F. Dean,Wang, Sinan,Wilson, David M.

supporting information, p. 2245 - 2255 (2021/08/12)

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