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4,5,6,7-tetrahydro-2-methylbenzothiazole-5-methanol
Base Information
- Chemical Name: 4,5,6,7-tetrahydro-2-methylbenzothiazole-5-methanol
- CAS No.: 77528-65-5
Factory Sells Best Quality 4,5,6,7-tetrahydro-2-methylbenzothiazole-5-methanol 77528-65-5 with ISO standards
- Molecular Formula: C9H13 N O S
- Molecular Weight: 183.274
- Vapor Pressure: 0.000111mmHg at 25°C
- Boiling Point: 323°C at 760 mmHg
- Flash Point: 149.2°C
- PSA： 61.36000
- Density: 1.191g/cm3
- LogP: 1.54870
4,5,6,7-tetrahydro-2-methylbenzothiazole-5-methanol(Cas 77528-65-5) Usage
InChI:InChI=1/C9H13NOS/c1-6-10-8-4-7(5-11)2-3-9(8)12-6/h7,11H,2-5H2,1H3
77528-65-5 Relevant articles
Synthesis of aminoiderivatives of 4,5,6,7-tetrahydro-benzothiazole. II. 4, 5 and 6-aminomethyl derivatives with cardiovascular activity
Maillard,Delaunay,Langlois,et al.
, p. 457 - 460 (2007/10/02)
The ethyl esters of 4,5,6,7-tetrahdyro-b...
4,5 or 6-Alkylaminoalkyl-2-alkyl-4,5,6,7-tetrahydro benzo[d]thiazoles
-
, (2008/06/13)
This invention relates to compounds of t...
77528-65-5 Process route
-
-
77528-64-4
methyl-2 ethoxycarbonyl-5 tetrahydro-4,5,6,7 benzo
thiazole
-
-
77528-65-5
methyl-2 N hydroxymethyl-5 tetrahydro-4,5,6,7 benzo
thiazole
| Conditions | Yield |
|---|---|
|
With
lithium aluminium tetrahydride;
In
diethyl ether;
for 35h;
Ambient temperature;
|
95%
|
-
-
7781-98-8
ethyl-3-hydroxybenzoate
-
-
77528-65-5
methyl-2 N hydroxymethyl-5 tetrahydro-4,5,6,7 benzo
thiazole
| Conditions | Yield |
|---|---|
|
Multi-step reaction
with
5
steps
1: 83 percent / H2
/ Ru/C / ethanol / 18 h / 120 °C / 75005.9 Torr
2: 93.5 percent / CrO3
, H2
SO4
/ acetone; H2
O / 5 - 10 °C
3: Br2
/ diethyl ether / 5 °C
4: 53 percent / dimethylformamide / 16 h / Ambient temperature
5: 95 percent / LiAlH4
/ diethyl ether / 35 h / Ambient temperature
With
chromium(VI) oxide; lithium aluminium tetrahydride; sulfuric acid; hydrogen; bromine;
Ru-carbon;
In
diethyl ether; ethanol; water; N,N-dimethyl-formamide; acetone;
|
77528-65-5 Upstream products
-
77528-64-4
methyl-2 ethoxycarbonyl-5 tetrahydro-4,5,6,7 benzo
thiazole -
33668-25-6
ethyl 3-oxocyclohexanecarboxylate
-
7781-98-8
ethyl-3-hydroxybenzoate
-
94160-25-5
hydroxy-3 cyclohexane carboxylate d'ethyle
77528-65-5 Downstream products
-
77528-66-6
methyl-2 tosyloxymethyl-5 tetrahydro-4,5,6,7 benzo
thiazole -
77528-67-7
methyl-2 N methylamino methyl-5 tetrahydro-4,5,6,7 benzo
thiazole